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Acromegaly refers to the enlargement of the distal acral parts of the body, including the hands, feet, chin, and nose. The enlargement is due to the overgrowth of cartilagemuscle, subcutaneous tissue, and skin. Thus, patients with acromegaly have a prominent jaw, a large nose, and large hands and feet, as well as enlargement of most other tissues, including the tongueheartliverand kidneys. In addition to the effects of excess GH, a pituitary tumour itself can cause severe headachesand pressure of the tumour on the optic chiasm can cause visual defects. Because the metabolic actions of GH are antagonistic opposite to those of insulin, some patients with acromegaly develop diabetes Dianabol. Other problems associated with acromegaly include high blood pressure hypertensionDbol pills, cardiovascular diseaseand arthritis. Dianabol with acromegaly also have an increased risk of developing malignant tumours of the large intestine. Some somatotroph tumours also produce prolactinwhich may cause abnormal lactation galactorrhea. Patients with acromegaly are usually treated by surgical resection of the pituitary tumour. They can also be treated with radiation therapy or with drugs such as pegvisomant, which blocks the binding of growth hormone to its receptors, and synthetic long-acting analogues of somatostatinwhich inhibit the secretion of GH. Growth hormone Article Media Additional Info. Article Contents.

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